Disease

Disease is one of the few status effects in RuneScape. It is caused by being damaged by zogres, skogres and fever spiders, from the scarabas during Dealing with Scarabas, by failing to pick the lock on a zogre coffin, or failing to cut a scrapey tree in Trouble Brewing.

When a player has disease (shown by an yellow hitsplat), the player's skills are reduced by a random amount that will take a very long time to wear off.

Wearing an inoculation brace can provide protection against disease, and will reduce the effects. Alternatively, the bathing in the thermal bath in Oo'glog will cure and briefly immunise players against disease.

Curing disease
Skills will gradually recover on their own, but for an instantaneous recovery, potions from Herblore can be used. Stat restore potions will recover Combat skills except Hitpoints and Prayer, while super restore potions will recover every skill except Hitpoints, including a limited amount of Prayer.

The effects of disease can be countered with Relicym's balm; drinking one or two doses will reduce the effect, while three will eliminate the disease altogether.

The unicorn stallion's 'Cure' effect cures both disease and poison, but requires some Summoning points.

Disease is cured upon death and respawn. It may be easier (and cheaper) to bank all items and get killed, or die in a safe minigame such as the duel arena.