Vespula

Vespula is one of the bosses encountered in The Chambers of Xeric. It is a parasite from the Abyss that Xeric and his followers stumbled upon when attempting to open a new dimensional tear.

Strategy
Use Protect from Magic, and attack with Ranged. Vespula can poison players starting at 20 damage, so a Serpentine helmet or another form of poison protection is highly recommended. In addition, septic tentacles will spawn near the entrance, dealing moderate poison damage (will not cause poison) to those who pass it.

The chamber contains Lux grubs, which need to be fed Medivaemia roots (found in the boss room). The grubs have an health bar, which will constantly degrade. If their health reaches 0, they will turn into Vespine soldiers, healing both Vespula and the portal. For this reason, it is recommended that at least one member of the team focuses solely on feeding Medivaemia roots to the grubs.

Alternatively, players can attack Vespula for 8 attacks with the blowpipe and then crossbow the portal once, before going back to attacking vespula for 8 more blowpipe attacks. This will prevent all but 1 of the Lux grubs from losing health. This may be a bug, and could potentially be fixed in a future update.

When Vespula reaches 20% of their health, she will stop flying, and can only be harmed with melee. During this time, the team should focus their attacks on the Abyssal portal. Ruby bolts can be very effective against the portal. After a short time, Vespula will go back to flying, and the team should refocus on her.

When the portal is destroyed, Vespula and the lux grubs automatically die.