Cave nightshade

Cave nightshade is used in Herblore to make Super strong weapon poison along with poison ivy berriesand coconut milk. This requires level 82 Herblore.

Players can eat nightshade, but this is not recommended in most situations, as this causes 150 life points of damage. When eaten the player's character will say, "Ahhhh! What have I done!"

 There are two spawns in the  Skavid caves  by the ogre city  Gu'Tanoth south of  Yanille. These spawns can be picked up without wearing gloves or gauntlets. Nightshade respawns between 30 and 60 seconds depending on how populated the world is. Higher populated worlds respawn nightshade faster than less populated worlds.