Antidote++ detail

Antidote++ (or Antipoison++) are made by mixing irit and magic roots in a vial of coconut milk, requiring 79 Herblore and giving 177.5 Herblore experience. Antidote++ potions cure poison and provide the second longest possible immunity to poison, which is 12 minutes (anti-venom+ provides immunity to poison for 15 minutes). This makes them far more useful than other types of anti-poisons, eliminating the need to drink constantly.

Drinking 2 doses of Antidote++ will cure venom. The first dose will reduce the venom to poison and the second will remove the poison.

This potion is widely used and known for being the cheapest and most efficient way to combat Venom and Poison.


Antidote++(4) Antidote++ (4)
Herblore icon Coins 25 High Level Alchemy icon -
177.5 XP 108 216 -
Herblore Herblore level 79
Antidote++ (unf) Antidote++ (unf) 1
Magic roots Magic roots 1

Production costs

Material Material cost Profit Profit/XP
Coconut milk Coconut milk 5,550 -5,266 -118.67
Coconut milk Coconut milk 5,550 -5,018 -56.54
Coconut milk Coconut milk 5,550 -4,601 -34.56
Coconut milk Coconut milk 5,550 -4,441 -25.02

Dropping monsters

Monster Combat level Quantity Rarity
Cave kraken 127 1 (noted) 3; Uncommon
Chaos Elemental 305 1 3; Uncommon
Kraken 291 2 (noted) 3; Uncommon
Venenatis 464 10 (noted) 3; Uncommon
Zulrah 725 10 (noted) 3; Uncommon
Corporeal Beast 785 40 (noted) 3; Uncommon
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