Cave nightshade detail

Cave nightshade is used in Herblore to make Weapon poison++ along with poison ivy berries and coconut milk. This requires level 82 Herblore.

Players can eat nightshade, but this is not recommended in most situations, as this causes 15 hitpoints of damage. When eaten the player's character will say, "Ahhhh! What have I done!" But as with most self-damaging items it's impossible to kill yourself with it, since the damage dealt scales with your current HP. (Note: It is possible to eat this without losing health - if the player were to accidentally eat the nightshade, they can teleport away and still have all their Hitpoints, provided they don't click "continue" on the dialogue text.)

There are two spawns in the Skavid caves by the ogre city Gu'Tanoth south of Yanille: the northern-most cave entrance, just south of the western entrance to Yanille, and the southern-most cave entrance within the city of Gu'Tanoth across a bridge. The Skavid map and a light source are needed to enter these caves (This requires partial completion of the Watchtower quest). These spawns can be picked up without wearing gloves or gauntlets, and respawns about every 52 seconds. Collecting a Cave Nightshade is a task in the Medium Ardougne Diary.

Nightshade may also be grown at Draynor Manor using the Farming skill and requires the player to wear gloves or gauntlets to successfully pick it. Bare-handed players won't be able to pick the nightshade and will also suffer a one-time poison damage for 2 hitpoints. Cave nightshade is grown from belladonna seeds. One seed can produce a minimum of 3 nightshades, where the Farming level reduces the chance of using up one of the three "lives" of the patch, much like harvesting herb patches.