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Iron knives can be made using the Smithing skill at level 22. One iron bar creates 5 iron knives and grants 25 Smithing experience. Buying iron bars and smithing them into knives is usually profitable depending on prices at the time. Like all knives, they have an incredibly fast fire rate, the same as darts. Along with bronze knives, which offer a similar range bonus as iron darts, they are considered to be one of the fastest and most efficient ways to gain early level Ranged experience. However, mithril darts have slightly better stats and range strength. Mithril darts are also cheaper, but lacks more of a square distance on ranging.

They can be bought from Martin Thwait's Lost and Found shop in the Rogues' Den.