The Lithkren Vault is an underground research facility located in the ruins of a dragonkin castle on Lithkren. During the Dragon Slayer II quest, it is opened with the dragon key, in which the player, Dallas Jones, and Bob inadvertently release the dragonkin Zorgoth and his creation, Galvek. Seven old notes are found here, of which four can only be obtained after completion of Dragon Slayer II.
In the north-east corner of the Vault, next to the pool, a machine can be found that can enchant a digsite pendant to allow players to teleport outside the Vault.
Adamant and rune dragons can also be found roaming the west and east wings of the facility, respectively, behind the red barriers. These barriers can only be entered once Dragon Slayer II has been completed.
The mural between the two metallic dragon chambers can be interacted with to check the player's killcount for those two dragons.
| Asgarnia |
Asgarnian Ice Dungeon • Dwarven Mine • Falador Mole Lair • Melzar's Maze • Mouse Hole • Taverley Dungeon |
| Kandarin |
Ancient Cavern • Ardougne Sewer • Chaos Druid Tower Dungeon • Clock Tower Dungeon • Eagles' Peak Dungeon • Elemental workshop • Goblin Cave • Mogre Camp (Port Khazard) • Observatory Dungeon • Temple of Ikov • Tower of Life Basement • Underground Pass • Waterfall Dungeon • White Wolf Mountain Caves • Witchaven Dungeon • Yanille Agility Dungeon |
| Karamja |
Ah Za Rhoon • Brimhaven Dungeon • Crandor and Karamja Dungeon • Karamjan Temple • Kharazi Dungeon • Pothole Dungeon • Rashiliyia's Tomb |
| Kharidian Desert |
Enakhra's Temple • Kalphite Lair • Smoke Dungeon • Sophanem Dungeon • Water Ravine Dungeon |
| Misthalin |
Digsite Dungeon • Dorgeshuun Mines • Draynor Sewers • Tolna's rift • Edgeville Dungeon • H.A.M. Hideout • Lumbridge Swamp Caves • Saradomin Shrine • Stronghold of Security • Tunnel of Chaos • Varrock Sewers |
| Morytania |
Abandoned Mine • Tarn's Lair • Barrows • Experiment cave • Shade Catacombs • Slayer Tower • Slepe Dungeon |
| Fremennik Province | |
| Feldip Hills | |
| Wilderness |
Deep Wilderness Dungeon • King Black Dragon Lair • Lava Maze Dungeon • Revenant Caves • Wilderness Agility Course Dungeon • Wilderness God Wars Dungeon |
| Zeah |
Catacombs of Kourend • Chambers of Xeric • Chasm of Fire • Crabclaw Caves • Lizardman Caves • Shayzien Crypts • The Warrens • Quidamortem Cave |
| Others |
Ape Atoll Dungeon • Dorgesh-Kaan South Dungeon • Dungeon (Player-owned house) • Entrana Dungeon • Evil Chicken's Lair • God Wars Dungeon • Grand Tree Tunnels • Jatizso mine • Lithkren Vault • Lunar Isle mine • Miscellania & Etceteria Dungeon • Mos Le'Harmless Caves • Temple of Marimbo Dungeon • Underwater Tunnel • Waterbirth Island Dungeon |