|385,500 per hour|
450 x Fire orb (588,150)
Fire orbs are worth 1,307 coins, and they are created by casting Charge Fire Orb on unpowered orbs at the Fire Obelisk. With a fire staff equipped, this requires three cosmic runes per cast (or 366 coins). Using Falador teleports for banking, players can charge 26 orbs per trip (one inventory slot is needed for the cosmic runes), resulting in a profit of 22,291 coins per trip.
The Fire Obelisk is located in the Taverley Dungeon. Using the map on the right as a guide through the dungeon, the round trip to the obelisk, counting banking, takes approximately 185 seconds using the 80 Agility shortcut, 205 seconds using the 70 Agility shortcut, or 325 seconds without any shortcuts.
Bear in mind that running through the Taverley Dungeon places you in combat range of aggressive black demons, hellhounds, poison spiders, and black dragons. A good Defence level is recommended. Also, having some Antipoison in your bank helps due to possible poisoning from the poisonous spiders.
Assuming the unpowered orbs and cosmic runes are purchased, you can make around 505 fire orbs an hour using the level 80 Agility shortcut (432,680 coins), 450 fire orbs using the level 70 Agility shortcut (385,470 coins), and 280 fire orbs using no shortcuts (239,945 coins).
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