|215,300 per hour|
750 x Bones to peaches (588,750)
Bones to peaches tablets are worth 785 coins and are generally in medium-high demand, they are used in place of food in some combat situations. The tablets are made on a Mahogany demon lectern in a player-owned house study. The most cost effective place to make tablets is at a house in Rimmington, where there is a nearby NPC named Phials who will un-note items for 5 coins each. To make tablets, move your POH to Rimmington and bring nature runes, noted soft clay, and coins. Find Phials, use the noted soft clay on him, and choose the third chat option to quickly un-note them. Then enter a POH through the house portal and enchant the tablets on a lectern.
Each trip you will make 24 bones to peaches tablets for 6,888 profit. On average, a round trip takes approximately 115-120 seconds, for a total of 720-750 tablets per hour, which leads to a 206,640 to 215,250 profit per hour.
An alternative to un-noting with Phials is to use a servant in your own player owned house. This is more costly, but allows you to stay at the lecturn, rather than spending time running to and from phials, increasing overall net profit. The calculations in this guide, however, were performed assuming you are using phials.
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