Poison spiders are monsters that can be found in many locations, including the Wilderness. They are aggressive and attack with Melee, being fairly accurate and able to inflict a poison that starts at a 6. Contrary to popular belief, Protect from Melee does not prevent them from causing poison. They are generally hated by players, as they make any location much more difficult to survive in.
- Observatory Dungeon (level 31)
- The Hollows (in the southwest cave under it)
- Taverley Dungeon
- Yanille Agility dungeon
Item Quantity Rarity GE market price Looting bag 1 Uncommon (1/30) Not sold Mysterious emblem 1 Rare (1/123) 68,122 Slayer's enchantment 1 Rare (1/268.8) 1,661