Poison spiders are monsters that can be found in many locations, including the Wilderness. They are aggressive and attack with Melee, being fairly accurate and able to inflict a poison that starts at a 6. Contrary to popular belief, Protect from Melee does not prevent them from causing poison. They are generally hated by players, as they make any location much more difficult to survive in.
The level 31 variant may be encountered during the Observatory Quest when searching chests for the goblin kitchen key.
These creatures pose a threat to players during the Family Crest quest during the battle with Chronozon.
Locations
- Observatory Dungeon (level 31)
- The Hollows (in the southwest cave under it)
- Taverley Dungeon
- Yanille Agility dungeon
- Wilderness:
- Edgeville Dungeon
- South of Callisto
- By the lever leading to the King Black Dragon Lair
- Lava Maze Dungeon
Drops
Item Quantity Rarity GE market price 
Looting bag 1 Uncommon (1/30)[1] Not sold
Mysterious emblem 1 Rare (1/123)[2] 163,851
Slayer's enchantment 1 Rare (1/268.8)[2] 928
- ↑ Only dropped by those found in the Wilderness.
- ↑ 2.0 2.1 Only dropped while on a slayer assignment given by Krystilia.
