A prayer enhance (+) is a potion that restores the player's prayer points over the course of 275 or 290 seconds, appearing to vary per player; those who get a game message in the chatbox that the potion is about to expire has the effect last for a total of 290 seconds. However, those that do not have the effect last for a total of 275 seconds. One prayer point is restored per 6 game ticks.

It can be made with 78 Herblore by using a buchu leaf with a water-filled gourd vial while having a cicely in the inventory. Making this potion gives 26.5 herblore experience.

This potion is the strong variant of the prayer enhance potions, and cannot be taken out of the Chambers of Xeric.