A stamina potion restores 20% of the player's run energy per dose and reduces the rate that run energy depletes while running by 70% for 2 minutes. This effect does not stack and its timer resets each time the player drinks a dose. When the stamina effect is active, the boot in the run energy orb turns orange from the usual yellow.
A stamina potion can be made with 77 Herblore by mixing a super energy potion with amylase crystals. One amylase crystal is required per dose, granting 25.5 Herblore experience each. Making a 3 dose potion gives 76.5 experience, whereas a 4 dose potion gives 102 experience. Players with 86 Herblore can mix caviar into a 2-dose stamina potion to create a 2-dose stamina mix.
Stamina potions are very useful in activities that require a lot of running, such as Runecrafting. With low weight, the reduced energy depletion will result in minimal loss of energy even with non-stop running, which the 20% restoration generally makes up for when taking another dose.